viper (version 1.6.0)

pruneRegulon: Prune Regulons

Description

This function limits the maximum size of the regulons

Usage

pruneRegulon(regulon, cutoff = 50, eliminate = FALSE)

Arguments

regulon

Object of class regulon

cutoff

Number indicating the maximum size for the regulons (maximum number of target genes)

eliminate

Logical whether regulons smalles than cutoff should be eliminated

Value

Prunned regulon

See Also

viper, msviper

Examples

data(bcellViper, package="bcellViper")
hist(sapply(regulon, function(x) sum(x$likelihood)/max(x$likelihood)), nclass=20)
preg <- pruneRegulon(regulon, 400)
hist(sapply(preg, function(x) sum(x$likelihood)/max(x$likelihood)), nclass=20)