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wateRmelon (version 1.16.0)

genkme: Internal functions for genotype-based normalization metrics

Description

genkme - genotype calling with 1d k-means

genkus - apply genkme to available SNPs

getsnp - grep the rs-numbered probes

gcose - calculate between-sample SNP standard error

gcoms - calculate between-sample SNP mean-squared deviation

Usage

genkme(y, peaks = c(0.2, 0.5, 0.8))

Arguments

y
a vector or matrix of numeric values (betas, between 0 and 1)
peaks
initial values for cluster positions

Value

see genki

Details

see genki

References

Pidsley R, Wong CCY, Volta M, Lunnon K, Mill J, Schalkwyk LC: A data-driven approach to preprocessing Illumina 450K methylation array data (submitted)