combineReplFromListToMatr

Suppose multiple measures (like multiple chanels) are taken for subjects and these measures are organized as groups in a list, 
like muliple parameters (= channels) or types of measurements (typically many paramters are recorded when screeinig compounds in microtiter plates).
Within one parameter/channel all replicate-data from separate list-entries ('lst') will get combined according to names of list-elements.
The function will trim any redundant text in names of list-elements, try to isolate separator (may vary among replicate-groups, but should be 1 character long).
eg names "hct116 1.1.xlsx" &amp; "hct116 1.2.xlsx" will be combined as replicates, "hct116 2.1.xlsx" will be considered as new group.

The efficient treatment and convenient analysis of experimental high-throughput (omics) data gets facilitated through this collection of diverse functions.
Several functions address advanced object-conversions, like manipulating lists of lists or lists of arrays, reorganizing lists to arrays or into separate vectors, merging of multiple entries, etc.
Another set of functions provides speed-optimized calculation of standard deviation (sd), coefficient of variance (CV) or standard error of the mean (SEM)
for data in matrixes or means per line with respect to additional grouping (eg n groups of replicates).
A group of functions facilitate dealing with non-redundant information, by indexing unique, adding counters to redundant or eliminating lines with respect redundancy in a given reference-column, etc.
Help is provided to identify very closely matching numeric values to generate (partial) distance matrixes for very big data in a memory efficient manner or to reduce the complexity of large data-sets by combining very close values.
Other functions help aligning a matrix or data.frame to a reference using partial matching or to mine an experimental setup to extract patterns of replicate samples.
Many times large experimental datasets need some additional filtering, adequate functions are provided.
Convenient data normalization is supported in various different modes, parameter estimation via permutations or boot-strap as well as flexible testing of multiple pair-wise combinations using the framework of 'limma' is provided, too.
Batch reading (or writing) of sets of files and combining data to arrays is supported, too.

Wolfgang Raffelsberger

wrMisc

Analyze Experimental High-Throughput (Omics) Data

combineReplFromListToMatr function

<dl><dt>lst</dt>
<dd>(list) list of arrays (typically multi-parameter measures of micortiterplate data)</dd>
<dt>silent</dt>
<dd>(logical) suppress messages</dd>
<dt>debug</dt>
<dd>(logical) additional messages for debugging</dd>
<dt>callFrom</dt>
<dd>(character) allow easier tracking of messages produced</dd></dl>

Arguments

Combine replicates from list to matrix — combineReplFromListToMatr

<dl>

<dt>lst</dt>
<dd>(list) list of arrays (typically multi-parameter measures of micortiterplate data)</dd>


<dt>silent</dt>
<dd>(logical) suppress messages</dd>


<dt>debug</dt>
<dd>(logical) additional messages for debugging</dd>


<dt>callFrom</dt>
<dd>(character) allow easier tracking of messages produced</dd>

</dl>

combineReplFromListToMatr: Combine replicates from list to matrix

Description

Usage

Value

Arguments

See Also

Examples