within cluster distance. If the distance between centroids of two clusters are smaller than this value, the clusters will be merged into one. Default value 100 bp.
out.distance
out of cluster distance. If the distance between centroids of two clusters are larger than this value, they are considered different binding sites. Default value 250 bp.
Value
A list where each element represents a chromosome. Within each chromosome, it is a data.frame with following fields
pos
consensus binding position.
nsig
number of significant original binding sites that are merged into consensus site.
origin
the origin of merged binding sites.
ori.pos
the original positions of merged binding sites. The consensus position is a weighted average of original positions.
Details
We group predicted locations from multiple conditions into clusters of close-by locations
by using agglomerative (bottom-up) hierarchical clustering with centroid linkage.
If the distance between centroids of two clusters are between in.distance and out.distance, the cluster with higher weight will be kept.