Maximum Likelihood Estimation of DNA Methylation and
Hydroxymethylation Proportions
Description
Maximum likelihood estimates (MLE) of the proportions
of 5-mC and 5-hmC in the DNA using information from BS-conversion,
TAB-conversion, and oxBS-conversion methods. One can use information from all three methods
or any combination of two of them. Estimates are based on Binomial model by
Qu et al. (2013) and
Kiihl et al. (2019) .