NTW (version 1.22.0)

P.preestimation: Pre-estimation of the transcriptional pertubation targets matrix P

Description

Pre-estimate the potential transcriptional perturbation targets matrix P according to gene expression data X . Those genes with the changes in top topK will be assumed as possible targets of the perturbations.

Usage

P.preestimation(X, topK)

Arguments

X

Gene expression data, a matrix with rows as genes and columns as experiments.

topK

The number of possible targets of the perturbations.

Value

A matrix with the same structure of X or P.

Examples

data(sos.data)
X<-sos.data
X<-as.matrix(X)
IX<-P.preestimation(X, topK= round(0.6*nrow(X)))
IX