Returns the log-maximum likelihood and the estimator of the mean under down-up profile with minimum at h
.
down.up(data,x,n.rep,h)
A vector containing the expressions of one gene.
A vector consisting of the average expression at time points (1, 2,… ,T), where T is the total number of time points.
A vector consisting of the number of replicate arrays at time points (1, 2,… ,T), where T is the total number of time points.
Down-up profile with minimum at h
.
Log-maximum likelihood
A vector containing the estimator of the mean
Liu, T., Lin, N., Shi, N. and Zhang, B. (2009), Information criterion-based clustering with order-restricted candidate profiles in short time-course microarray experiments. BMC Bioinformatics, 10: 146.
Robertson, T., Wright, F. T. and Dykstra, R. L. (1988). Order restricted statistical inference. New York: Wiley.
Shi, N., Gao, W. and Zhang, B. (2001). One sided estimation and testing problems for location models from grouped samples. Commun Statist-Simula, 30: 885-898.