ORIClust (version 1.0-1)

isodecre: isodecre

Description

Isotonic regression of a with weights w under monotone decreasing profile.

Usage

isodecre(a, w)

Arguments

a

A vector consisting of the average expression at time points (1, 2,… ,T), where T is the total number of time points.

w

The weights.

Value

is

A vector containing the estimator of the mean

References

Liu, T., Lin, N., Shi, N. and Zhang, B. (2009), Information criterion-based clustering with order-restricted candidate profiles in short time-course microarray experiments. BMC Bioinformatics, 10: 146.

Robertson, T., Wright, F. T. and Dykstra, R. L. (1988). Order restricted statistical inference. New York: Wiley.

Shi, N., Gao, W. and Zhang, B. (2001). One sided estimation and testing problems for location models from grouped samples. Commun Statist-Simula, 30: 885-898.