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RANKS (version 1.1)

Ranking of Nodes with Kernelized Score Functions

Description

Implementation of Kernelized score functions and other semi-supervised learning algorithms for node label ranking to analyze biomolecular networks. RANKS can be easily applied to a large set of different relevant problems in computational biology, ranging from automatic protein function prediction, to gene disease prioritization and drug repositioning, and more in general to any bioinformatics problem that can be formalized as a node label ranking problem in a graph. The modular nature of the implementation allows to experiment with different score functions and kernels and to easily compare the results with baseline network-based methods such as label propagation and random walk algorithms, as well as to enlarge the algorithmic scheme by adding novel user-defined score functions and kernels.

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Version

Install

install.packages('RANKS')

Monthly Downloads

216

Version

1.1

License

GPL (>= 2)

Maintainer

Giorgio Valentini

Last Published

September 20th, 2022

Functions in RANKS (1.1)

do.GBA

GBA cross-validation experiments with multiple classes
Utilities

Utility functions
label.prop

Label propagation
ker.score.cv

RANKS cross-validation for a single class
kernel.functions

Kernel functions
ker.score.classifier.cv

Multiple cross-validation with RANKS for classification
multiple.RW.cv

Random walk, GBA and labelprop multiple cross-validation for a single class
do.RWR

Random walk with restart cross-validation experiments with multiple classes
ker.score.classifier.holdout

RANKS held-out procedure for a single class
multiple.ker.score.cv

RANKS multiple cross-validation for a single class
do.loo.RANKS

RANKS leave-one-out experiments with multiple classes
find.optimal.thresh.cv

Function to find the optimal RANKS score thereshold
score.multiple.vertex-methods

Multiple vertex score functions
score.single.vertex-methods

Single vertex score functions
weighted.score.multiple.vertex-methods

Multiple vertex score functions - weighted version
weighted.score.single.vertex-methods

Single vertex score functions - weighted version
multiple.ker.score.thresh.cv

Function for RANKS multiple cross-validation and optimal threshold finding for a single class
rw.kernel-methods

Random walk kernel
RANKS-package

RANKS: Ranking of Nodes with Kernelized Score Functions
do.RW

Random walk cross-validation experiments with multiple classes
do.RANKS

RANKS cross-validation experiments with multiple classes
RW

Random walk on a graph
RW.cv

Random walk, GBA and labelprop cross-validation for a single class
GBAsum

Guilt By Association (GBA) using the sum rule
GBAmax

Guilt By Association (GBA) using the maximum rule
RWR

Random walk with Restart on a graph