RNOmni (version 0.4.0)

BAT: Basic Association Test

Description

Test of association between genotype and the untransformed phenotype, adjusting for covariates and population structure.

Usage

BAT(y, G, X, S, parallel = F, check = T)

Arguments

y

Numeric phenotype vector.

G

Obs by snp genotype matrix.

X

Model matrix of covariates.

S

Model matrix of structure adjustments.

parallel

Logical indicating whether to run in parallel. Must register parallel backend first.

check

Logical indicating whether to check input formatting.

Value

A numeric matrix of score statistics and p-values, one for each locus (column) in G, assessing the null hypothesis that genotype is unrelated to the phenotype.

Examples

# NOT RUN {
# BAT against normal phenotype
p = RNOmni::BAT(y=RNOmni::Y[,1],G=RNOmni::G[,1:10],X=RNOmni::X,S=RNOmni::S);
# }