Refines the initial mapping with more complex models that allow gene expression to vary quantitatively across bins (instead of 'on' or 'off'), and that also considers the covariance structure between genes.
RefinedMapping(object, genes.use)Seurat object
Genes to use to drive the refinement procedure.
Seurat object, where mapping probabilities for each bin are stored in object@final.prob
Full details given in spatial mapping manuscript.