Methods for validating the legitimacy of two specific clusters using classification. SVMs are used as the basis for the classification. Merging is done based on the connectivity from an SNN graph.
ValidateSpecificClusters(object, cluster1 = NULL, cluster2 = 1,
pc.use = 2, top.genes = 30, acc.cutoff = 0.9)Seurat object
First cluster to check classification
Second cluster to check with classification
Which PCs to use for model construction
Use the top X genes for model construction
Accuracy cutoff for classifier
Returns a Seurat object, object@ident has been updated with new cluster info