calc_null_loglik

Return the log-likelihood of the data betahat, with
 standard errors betahatsd, under the null that beta==0

The R package 'ashr' implements an Empirical Bayes
approach for large-scale hypothesis testing and false discovery
rate (FDR) estimation based on the methods proposed in
M. Stephens, 2016, "False discovery rates: a new deal",
<DOI:10.1093/biostatistics/kxw041>. These methods can be applied
whenever two sets of summary statistics---estimated effects and
standard errors---are available, just as 'qvalue' can be applied
to previously computed p-values. Two main interfaces are
provided: ash(), which is more user-friendly; and ash.workhorse(),
which has more options and is geared toward advanced users. The
ash() and ash.workhorse() also provides a flexible modeling
interface that can accommodate a variety of likelihoods (e.g.,
normal, Poisson) and mixture priors (e.g., uniform, normal).

Peter Carbonetto

ashr

Methods for Adaptive Shrinkage, using Empirical Bayes

Matthew Stephens

Chaoxing Dai

David Gerard

Mengyin Lu

Lei Sun

Jason Willwerscheid

Nan Xiao

Mazon Zeng

calc_null_loglik function

<dl><dt>data</dt>
<dd>a data object; see set_data</dd></dl>

Arguments

Compute loglikelihood for data under null that all beta are 0 — calc_null_loglik

<dl>

<dt>data</dt>
<dd>a data object; see set_data</dd>

</dl>

Compute loglikelihood for data under null that all beta are 0

calc_null_loglik: Compute loglikelihood for data under null that all beta are 0

Description

Usage

Arguments