mirIntegrator (version 1.2.0)

mirTarBase: MicroRNA-target interactions in human.

Description

Dataset of miRNA-target interactions in human obtained from mirTarBase release 4.5: Nov. 1, 2013.

Usage

data(mirTarBase)

Value

A data.frame with human miRNA-targets interactions

Format

A data.frame with 39083 interactions and 9 variables. The columns needed for this package are:

• miRNA: which contains the miRNA ID,
• Target.ID: contains the entrez ID of the gene targeted by the miRNA

Source

Downloaded from http://mirtarbase.mbc.nctu.edu.tw/ on 4/1/2015. A script which downloads the file and constructs the mirTarBase object may be found in 'inst/scripts/get_mirTarBase.R', see the example.

Details

This dataset is licensed by its authors (Hsu et al.), see http://mirtarbase.mbc.nctu.edu.tw/cache/download/LICENSE.

References

S.-D. Hsu, Y.-T. Tseng, S. Shrestha, Y.-L. Lin, A. Khaleel, C.-H. Chou, C.-F. Chu, H.-Y. Huang, C.-M. Lin, S.-Y. Ho, T.-Y. Jian, F.-M. Lin, T.-H. Chang, S.-L. Weng, K.-W. Liao, I.-E. Liao, C.-C. Liu, and H.-D. Huang, miRTarBase update 2014: an information resource for experimentally validated miRNA-target interactions, Nucleic Acids Research, vol. 42, pp. D78 - D85, Jan. 2014.

Examples

data(mirTarBase)
head(mirTarBase)

script <- system.file("scripts", "get_mirTarBase.R", 
                      package = "mirIntegrator")
script
readLines(script)