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mixOmics (version 2.8-1)

Integrate Omics data project

Description

The package supplies two efficients methodologies: regularized CCA and sparse PLS to unravel relationships between two heterogeneous data sets of size (nxp) and (nxq) where the p and q variables are measured on the same samples or individuals n. These data may come from high throughput technologies, such as omics data (e.g. transcriptomics, metabolomics or proteomics data) that require an integrative or joint analysis. However, mixOmics can also be applied to any other large data sets where p + q >> n. rCCA is a regularized version of CCA to deal with the large number of variables. sPLS allows variable selection in a one step procedure and two frameworks are proposed: regression and canonical analysis. Numerous graphical outputs are provided to help interpreting the results.

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Version

Install

install.packages('mixOmics')

Monthly Downloads

280

Version

2.8-1

License

GPL (>= 2)

Maintainer

Kim-Anh Cao

Last Published

August 12th, 2010

Functions in mixOmics (2.8-1)

image

Plot the cross-validation score.
breast.tumors

Human Breast Tumors Data
imgCor

Image Maps of Correlation Matrices between two Data Sets
plot.rcc

Canonical Correlations Plot
plot3dVar

Plot of Variables in three dimensions
pca

Principal Components Analysis
jet.colors

Jet Colors Palette
map

Converts an indicator matrix to class vector
estim.regul

Estimate the parameters of regularization for Regularized CCA
multidrug

Multidrug Resistence Data
plotVar

Plot of Variables
cim

Clustered Image Maps (CIMs) ("heat maps")
liver.toxicity

Liver Toxicity Data
linnerud

Linnerud Dataset
nutrimouse

Nutrimouse Dataset
plsda

Partial Least Squares Discriminate Analysis (PLS-DA).
print

Print Methods for CCA, (s)PLS and Summary objects
splsda

Sparse Partial Least Squares Discriminate Analysis (sPLS-DA)
srbct

Small version of the small round blue cell tumors of childhood data
scatterutil

Graphical utility functions from ade4
rcc

Regularized Canonical Correlation Analysis
spls

Sparse Partial Least Squares (sPLS)
s.match

Plot of Paired Coordinates
unmap

Converts a class vector to an indicator matrix
valid

Compute validation criterion for PLS and Sparse PLS
plotIndiv

Plot of Individuals (Experimental Units)
vip

Variable Importance in the Projection (VIP)
pls

Partial Least Squares (PLS) Regression
mat.rank

Matrix Rank
summary

Summary Methods for CCA and PLS objects
nipals

Non-linear Iterative Partial Least Squares (NIPALS) algorithm
predict

Predict Method for PLS, sparse PLS, PLSDA Regression or Sparse PLSDA
network

Relevance Network for (Regularized) CCA and (sparse) PLS regression
internal-functions

Regularized CCA Internal Functions
plot3dIndiv

Plot of Individuals (Experimental Units) in three dimensions