occugene (version 1.32.0)

etDelta: Number of New ORF Knockouts

Description

Estimates the number of new knockouts in next d clones.

Usage

etDelta(d,anno,clone)

Arguments

d

number of new clones

anno

2-column matrix of annotation

clone

vector

Value

expected

Expected value

variance

Variance

Details

Estimates the number of new ORF knockouts in the next d clones using the method outlined by Efron and Thisted.

References

See the book chapter O. Will (**) in ** and also Efron, B. and Thisted, R. (1976) Estimating the number of unseen species: How many words did Shakespere know? Biometrika. 63, 435-447.

Examples

data(sampleAnnotation)
data(sampleInsertions)
a.data <- sampleAnnotation
experiment <- sampleInsertions
orf <- cbind(a.data$first,a.data$last)
clone <- experiment$position
etDelta(10,orf,clone)