pkr (version 0.1.3)

plotPK: Plot concentration vs. time curve for individuals and collectively.

Description

Generates individual and superposed concentration vs. time curve and save it in pdf files.

Usage

plotPK(concData, id, Time, conc, unitTime = "hr", unitConc = "ng/mL", trt = "", 
       fit = "Linear", dose = 0, adm = "Extravascular", dur = 0, outdir = "Output")

Arguments

concData

name of data table containing time-concentration data of multiple subjects

id

column name for subject ID

Time

column name for the time

conc

column name for the concentration

unitTime

unit for the time

unitConc

unit for the concentration

trt

column name for the treatment code. This is useful for crossover study like bioequivalence trial.

fit

one of "Linear" or "Log" to indicate the way to calculate AUC

dose

administered dose. One should be careful for the unit. This can be a vector containing dose for each subject in order.

adm

one of "Bolus" or "Infusion" or "Extravascular" to indicate drug administration mode

dur

infusion duration for constant infusion, otherwise 0. This can be a vector containing values for each subject in order.

outdir

name of the folder to be used for the output files

Value

This function saves pdf files and tiff files in the outdir folder.

Details

This function generates plots for individual and summary concentration vs. time curve. This function calles NCA().

See Also

NCA

Examples

# NOT RUN {
# plotPK(Theoph, "Subject", "Time", "conc", unitTime="hr", unitConc="mg/L", dose=320)
# plotPK(Indometh, "Subject", "time", "conc", unitTime="hr", unitConc="mg/L", adm="Bolus", dose=25)
# }