curtail

Calculates the probability to declare efficacy at the end of study given the Z value at the current look

S4 class object for creating and managing group sequential designs. It calculates the efficacy and futility boundaries at each look. It allows modifying the design and tracking the design update history.

Hui Zheng

seqmon

Group Sequential Design Class for Clinical Trials

curtail function

<dl> <dt>lower.boundary</dt>
<dd>lower boundaries
</dd> <dt>upper.boundary</dt>
<dd>upper boundaries
</dd> <dt>look</dt>
<dd>current look number
</dd> <dt>t</dt>
<dd>time of looks
</dd> <dt>noncen</dt>
<dd>noncentrality parameter
</dd> <dt>current</dt>
<dd>current Z statistic
</dd></dl>

Arguments

Generic function that calculates the probability to declare efficacy at the end of study given the Z value at the current look
 — curtail

<dl>

 <dt>lower.boundary</dt>
<dd>lower boundaries
</dd>

 <dt>upper.boundary</dt>
<dd>upper boundaries
</dd>

 <dt>look</dt>
<dd>current look number
</dd>

 <dt>t</dt>
<dd>time of looks
</dd>

 <dt>noncen</dt>
<dd>noncentrality parameter
</dd>

 <dt>current</dt>
<dd>current Z statistic
</dd>

</dl>

Generic function that calculates the probability to declare efficacy at the end of study given the Z value at the current look

curtail: Generic function that calculates the probability to declare efficacy at the end of study given the Z value at the current look

Description

Usage

Value

Arguments

Examples