Compute the modified Haybittle-Peto boundary for the final look
mHP.c(mu = c(0, 0, 0), v = c(1, 2, 3), b = 3, alpha = 0.05,
eps = 1/2, side = c("one", "two"))the mean vector
The variance vector, usually proportional to information in calendar time
The (constant) modified Haybittle-Peto boundary, typically computed
by mHP.b
The significance level desired
The fraction of alpha to use
one-sided or two-sided (one or two)
the modified Haybittle-Peto boundary for the final look
Compute the modified Haybittle-Peto boundary for the final look
Lai, Tze Leung and Lavori, Philip W. and Shih, Mei-Chiung. Sequential Design of Phase II-III Cancer Trials, Statistics in Medicine, Volume 31, issue 18, p.1944-1960, 2012.