bScore

masterPlate

the treatment experiment condition in EXPERIMENT_MODIFICATION

treatment

the control experiment condition in EXPERIMENT_MODIFICATION

control

should calculated B-score files be written to the current folder? File names is (masterPlate).bscore.csv.

outFile

Calculate the B-score for plates belonging to the same master plate.
Positive / negative controls are removed from the calculation.

Select hits from synthetic lethal RNAi screen data. For
        example, there are two identical celllines except one gene is
        knocked-down in one cellline. The interest is to find genes
        that lead to stronger lethal effect when they are knocked-down
        further by siRNA. Quality control and various visualisation
        tools are implemented. Four different algorithms could be used
        to pick up the interesting hits. This package is designed based
        on 384 wells plates, but may apply to other platforms with
        proper configuration.

bScore: Calculate B-score

Description

Usage

Arguments

Value

References

Examples