Hits Selection for Synthetic Lethal RNAi Screen Data
Description
Select hits from synthetic lethal RNAi screen data. For
example, there are two identical celllines except one gene is
knocked-down in one cellline. The interest is to find genes
that lead to stronger lethal effect when they are knocked-down
further by siRNA. Quality control and various visualisation
tools are implemented. Four different algorithms could be used
to pick up the interesting hits. This package is designed based
on 384 wells plates, but may apply to other platforms with
proper configuration.