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RRate (version 1.0)

Estimating Replication Rate for Genome-Wide Association Studies

Description

Replication Rate (RR) is the probability of replicating a statistically significant association in genome-wide association studies. This R-package provide the estimation method for replication rate which makes use of the summary statistics from the primary study. We can use the estimated RR to determine the sample size of the replication study, and to check the consistency between the results of the primary study and those of the replication study.

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Version

Install

install.packages('RRate')

Monthly Downloads

114

Version

1.0

License

GPL-3

Maintainer

Wei Jiang

Last Published

August 17th, 2016

Functions in RRate (1.0)

RRate-functions

Estimating Replication Rate for primary associations
RRate-package

\Sexpr[results=rd,stage=build]{tools:::Rd_package_title("#1")}RRateEstimating Replication Rate for Genome-Wide Association Studies
repSampleSizeRR

Sample size determination for the replication study based on RR
HLtest

Hosmer-Lemeshow test
SEest

Estimating standard error of the observed log-odds ratio
smryStats

Example summary statistics