The package can prioritize candidate disease metabolites based
on global functional relationships between metabolites in the
context of metabolic pathways
Description
The package can prioritize the candidate disease metabolites based on the assumption
that functionally related metabolites tend to associate with the same or similar
diseases in the context of metabolic pathway. The PROFANCY package (1) prioritizes the
disease metabolites from global functional similarity and local modularity of the
metabolic network; (2) allows users to select default metabolites or input their
interested metabolites as seed nodes or candidate nodes (3) can prioritize the candidate
metabolites in KEGG or EHMN metabolic network.